Largo, FL Hotel In the Heart of Tampa Bay You'll find the comfort and convenience you need at our Holiday Inn Express® Largo - Clearwater hotel, one of the leading Largo, Florida hotels located in the heart of Tampa Bay. Along with easy access to Tampa International Airport and St. Petersburg-Clearwater International Airport, we also provide a central location near major attractions and businesses. Whether touring Largo Central Park or viewing summer concerts at Largo Cultural Center, activities abound near our Largo, FL hotel. Enjoy the small-town atmosphere of Largo while at Pinellas Trail where you and your family can bike or jog the 30-plus miles of trails. Use our hotel's convenient location in Largo, FL as a starting point for day trips to St. Petersburg's Salvador Dali Museum, Tampa's Busch Gardens or Walt Disney® World in Orlando.